A list of regular Neighbours characters from the 2010 season, organised by the number of episodes they were featured in. In 2010, a total of 235 episodes were broadcast.

1. Toadfish Rebecchi (152 episodes)
2. Andrew Robinson (139 episodes)
=2. Declan Napier (139 episodes)
=2. Kate Ramsay (139 episodes)
5. Lucas Fitzgerald (137 episodes)
6. Donna Freedman (134 episodes)
7. Susan Kennedy (126 episodes)
=7. Summer Hoyland (126 episodes)
9. Karl Kennedy (121 episodes)
10. Steph Scully (114 episodes)
11. Libby Kennedy (111 episodes)
12. Lyn Scully (102 episodes)
=12. Paul Robinson (102 episodes)
14. Zeke Kinski (100 episodes)
15. Rebecca Robinson (96 episodes)
16. Natasha Williams (88 episode)
17. Callum Jones (83 episodes)
18. Sophie Ramsay (80 episodes)
19. Michael Williams (78 episodes)
20. Ringo Brown (65 episodes)
21. Harry Ramsay (63 episodes)
22. Sonya Mitchell (60 episodes)
23. India Napier (47 episodes)
=23. Lou Carpenter (47 episodes)
25. Chris Pappas (41 episodes)**
26. Ben Kirk/Fitzgerald (34 episodes)
27. Charlie Hoyland (33 episodes)
31. Mark Brennan (21 episodes)
32. Kyle Canning (13 episodes)**
31. Jade Mitchell (3 episodes)
32. Daniel Fitzgerald (1 episode)*

** Although only a guest character during the 2010 season, this character would later return as part of the regular cast
* Although only a guest character during the 2010 season, this character was previously a part of the regular cast