A list of regular Neighbours characters from the 1999 season, organised by the number of episodes they were featured in. In 1999, a total of 225 episodes were broadcast.

1. Harold Bishop (128 episodes)
2. Karl Kennedy (125 episodes)
3. Susan Kennedy (121 episodes)
4. Madge Bishop (115 episodes)
5. Lou Carpenter (109 episodes)
6. Philip Martin (107 episodes)
7. Amy Greenwood (105 episodes)
8. Drew Kirk (104 episodes)
=8. Paul McClain (104 episodes)
10. Joel Samuels (99 episodes)
11. Tad Reeves (98 episodes)
12. Lance Wilkinson (95 episodes)
=12. Libby Kennedy (95 episodes)
14. Bill Kennedy (94 episodes)
15. Toadfish Rebecchi (93 episodes)
16. Anne Wilkinson (92 episodes)
17. Ruth Wilkinson (90 episodes)
18. Hannah Martin (63 episodes)
19. Sarah Beaumont (57 episodes)
20. Louise Carpenter (24 episodes)
21. Mike Healey (22 episodes)
22. Teresa Bell (16 episodes)
23. Lyn Scully (15 episodes)
24. Joe Scully (14 episodes)
25. Michelle Scully (13 episodes)
26. Felicity Scully (12 episodes)
=26. Stephanie Scully (12 episodes)
28. Daniel Fitzgerald (3 episodes)*
29. Sally Upton (2 episodes)

* Although only a guest character during the 1999 season, this character later returned as part of the regular cast