A list of regular Neighbours characters from the 2000 season, organised by the number of episodes they were featured in. In 2000, a total of 235 episodes were broadcast.

1. Susan Kennedy (136 episodes)
2. Karl Kennedy (131 episodes)
3. Harold Bishop (130 episodes)
4. Stephanie Scully (129 episodes)
5. Toadfish Rebecchi (126 episodes)
6. Lyn Scully (125 episodes)
7. Felicity Scully (122 episodes)
8. Lou Carpenter (121 episodes)
9. Joe Scully (117 episodes)
=9. Lance Wilkinson (117 episodes)
11. Tad Reeves (114 episodes)
12. Paul McClain (113 episodes)
13. Libby Kennedy (110 episodes)
=13. Drew Kirk (110 episodes)
15. Joel Samuels (105 episodes)
16. Teresa 'Tess' Bell (103 episodes)
17. Michelle Scully (101 episodes)
18. Dione Bliss (91 episodes)
19. Madge Bishop (77 episodes)
20. Louise Carpenter (39 episodes)
21. Anne Wilkinson (31 episodes)
22. Daniel Fitzgerald (29 episodes)*
23. Amy Greenwood (22 episodes)
24. Bill Kennedy (20 episodes)
25. Darcy Tyler (8 episodes)

* Although only guest characters during the 2000 season, these characters would later be part of the regular cast

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